Možda će vas i ovo zanimati:
http://www.ncbi.nlm.nih.gov/pubmed/21315341
Fertil Steril. 2011 Feb 10. [Epub ahead of print]
Follicle-stimulating hormone administered at the time of human chorionic gonadotropin trigger improves oocyte developmental competence in in vitro fertilization cycles: a randomized, double-blind, placebo-controlled trial.
Lamb JD, Shen S, McCulloch C, Jalalian L, Cedars MI, Rosen MP.
Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Reproductive Endocrinology and Infertility, University of California, San Francisco, California.

Abstract
OBJECTIVE: To determine whether an additional follicle-stimulating hormone (FSH) bolus administered at the time of the human chorionic gonadotropin (hCG) trigger can improve the developmental competence of the oocyte.
DESIGN: Randomized, double-blind, placebo-controlled, clinical trial.
SETTING: Academic medical center.
PATIENT(S): Women undergoing a long agonist suppression in vitro fertilization (IVF) protocol for treatment of infertility.
INTERVENTION(S): FSH bolus at time of hCG trigger versus placebo.
MAIN OUTCOME MEASURE(S): Primary outcome; fertilization; secondary outcomes: oocyte recovery, implantation rate, and clinical and ongoing pregnancy/live birth rates.
RESULT(S): A total of 188 women (mean age: 36.2 years; range: 25 to 40 years) were randomized. Fertilization (2PN/#oocyte) was statistically significantly improved in the treatment arm (63% vs. 55%) as was the likelihood of oocyte recovery (70% vs. 57%). There was no statistically significant difference in clinical pregnancy rate (56.8% vs. 46.2%) or ongoing/live birth rate (51.6% vs. 43.0%).
CONCLUSION(S): Improvements in IVF success rates have largely been due to optimization of embryo culture and stimulation protocols; less attention has been directed toward methods to improve induction of final oocyte maturation. This was the first randomized, double-blind, placebo-controlled trial to modify the ovulation trigger to improve oocyte competence, as demonstrated by the statistically significant improvement in fertilization.


http://www.ncbi.nlm.nih.gov/pubmed/20542507
Fertil Steril. 2011 Feb;95(2):538-41. Epub 2010 Jun 9.
Pressure changes during embryo transfer.
Grygoruk C, Sieczynski P, Pietrewicz P, Mrugacz M, Gagan J, Mrugacz G.
Center for Reproductive Medicine BOCIAN, Bialystok Technical University, Bialystok, Poland. cezary.grygoruk@gmail.com

Abstract
OBJECTIVE: To investigate the pressure changes in the transferred load during mock ET.
DESIGN: Experimental setup.
SETTING: Academic Research Institute of Mechanical Engineering and private centers of reproductive medicine. PATIENTS(S): None.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Laboratory simulations of ET into a rigid transparent uterine model equipped with a pressure sensor.
RESULT(S): Injection of a transferring load during mock ET could increase pressure locally up to 155 mm Hg in <0.1 seconds. The recorded pressure increase slope reached values as high as 72,000 mmHg/s, and the pressure decrease slope reached 144,000 mmHg/s. The pressure buildup in the transferred liquid was proportional to the ejection speed of the transferred load.
CONCLUSION(S): ET can cause rapid pressure fluctuations in the transferred liquid. Therefore, it is advisable to transfer the embryo gently with minimum ejection speed, to avoid exposing the embryo to the steep pressure gradient.