CANCER INCIDENCE AFTER INFERTILITY AND IVF
pozdrav svima, nova sam na forumu
zelim da podelim sa vama ono sto znam
naime, moja majka ima rak jajnika, a i baka mi je imala rak genitalnih organa. zato sam vrlo oprezna i nepoverljiva u pogledu hormona, i vrlo temeljita kad treba da se informisem.
sledeci tekst razmatra u kakvom su odnosu kancer-ivf kod zena koje su se lecile od steriliteta i primale hormone
izvor
http://www.pregnancymd.org/assisted-hatching.htm
iz australije
PregnancyMD's Resources. A full range of information on ART ...
Assisted Hatching is a Laboratory procedure whereby the shell (zona pellucida)
... The Assisted Hatching technique was commenced in 1990 by a team led by Dr ...
www.pregnancymd.org/assisted-hatching.htm - 24k
CANCER INCIDENCE AFTER INFERTILITY AND IVF
Doctors have used fertility drugs since the 1960's. These were used to stimulate the ovaries to produce eggs and were found to be successful. In the past 20 years the usage of these fertility medications has greatly increased with the development of IVF and related procedures.
The question of whether women exposed to fertility drugs might be associated with an increased risk of cancers, has attracted a lot of attention. A large multi-centred study has now concluded that these medications are safe.
The Research Team
The researchers were Dr Alison Venn, Ms Lyn Watson, Ms Fiona Bruinsma, Centre for the Study of Mothers'and Childrens Health, La Trobe University; Professor Graham Giles, Cancer Epidemiology Centre, Anti-Cancer Council of Victoria; and Professor David Healy, Monash IVF & Dep't of Obstetrics & Gynaecology, Monash University
The Study
The study uses the term IVF to include other related treatments such as GIFT& ICSI.
The study was designed to clarify whether there was any increase in the numbers of cancers of the breast, ovary and uterus in women on IVF compared with the numbers expected among women of the same age followed up over the same period in the general population.
In the event that there were more of these cancers than predicted, what explanations might be plausible.
The study followed up 29,700 women who were referred to any of 10 participating Australian IVF clinics between 1978 & 1993. It is the largest study of its type in the world.
Treated Group 20,656 women received fertility drugs during IVF treatment.
Untreated Group 9,044 women did not receive fertility drugs during IVF treatment
The duration of follow up ranged from 1 to 22 years, with the majority followed up for 5 to 10 years.
What did the study find?
Cancers of the breast and ovary were no more common in IVF patients overall than in the general population.
Cancers of the uterus were more common than predicted in untreated IVF patients but were no more common than predicted in the significant finding disappeared with time. This can be explained by the fact that these women were incubating breast cancer at the time of commencement of treatment which then showed up because of the medications. These women would have shown up with breast cancer but a short while later.
Women with infertility for which a cause could not be found had more cancers of the ovary and uterus than predicted, whether or not they had treatment with fertility drugs. These cancers were therefore not caused by the medications.
There was no evidence of any link between the number of treatment cycles or type of fertility drug used and cancer incidence.
Conclusions
The findings provide reassurance that the incidence of breast and ovarian cancers in IVF patients is the same as that for women of the same age in the general population when considered over a five to ten year period. treated group.
More women than predicted in the treated group had a breast cancer diagnosed in the first year after treatment with fertility drugs. This statistically
The evidence of increased numbers of cancers above the predicted in small numbers of women in particular sub-groups needs further study. The occurrence of above expected numbers of breast cancer in the first year after treatment is consistent with other research showing a small increase in diagnoses of breast cancer shortly after women give birth. The same effect has been seen in recent users of the oral contraceptive pill and hormone replacement therapy. Possible explanations for this finding after IVF treatment include earlier detection of abnormal breast changes due to close medical supervision, the biological effects of fertility drugs, or both. Explanations for the relationship between unexplained infertility and the increase in ovarian and uterine cancer are harder to come by.
To explore such issues, the research team has started a more detailed investigation of about 700 IVF patients some of whom have cancer and others who do not.
sa istog sajta
Clomiphene (Clomid/Serophene
This oral drug is used to stimulate the pituitary to stimulate the production of extra oocytes. Occasionally side effects like headache, weariness, occasional visual disturbance and hot flushes may be noticed after a few days on this drug. These cease as soon as patients stop taking it..
Some patients who have used Clomiphene have suffered breast and ovarian cancers in later life but there is no proven association between the use of Clomiphene and cancer. (*NOTE: women who delay child bearing until later in life or those who do not have children also have a higher incidence of breast and ovarian cancer in later life and Clomiphene users are in these groups). For further information try Infertility and Drugs.
p.s. sajt je odlican, pregledan, naucila sam dosta citajuci ga. savetovala bih svima da ga procitaju.
osim toga skinula sam dosta sa njega, mogu poslati mailom kome treba ili moderatorki da proceni da li je potrebno negde ga okaciti.
