S wiki o slobodnom i vezanom T4. Čemu služi T4 ste vjerojatno čitale, katalitička funkcija u metabolizmu itd.
Moram priznati da mene ta tema nije do sada baš zanimala, ali gledam simptome raznoraznih boleština, zbilja se ne vidim tu nigdje. Ali recimo da uvijek postoji neki početak pa sam možda tu negdje.
Most of the thyroid hormone circulating in the blood is bound to transport proteins. Only a very small fraction of the circulating hormone is free (unbound) and biologically active, hence measuring concentrations of free thyroid hormones is of great diagnostic value.
When thyroid hormone is bound, it is not active, so the amount of free T3/T4 is what is important. For this reason, measuring total thyroxine in the blood can be misleading.