Jos jedna stvar koju treba uzeti u obzir; postoji "unfractionated heparin" (UFH) i "low molecular weight heparin" (LMWH). Koliko sam pronasla kazu da LMWH ima manje nuspojave - manja vjerojatnost trombocitopeniji i smanjenja gustoce kostiju od UFH.
Fragmin je LMWH.


A evo i jedne svjezije studije:
http://www.ncbi.nlm.nih.gov/pubmed/18664969?ordinalpos=1&itool=EntrezSystem2.PEntrez. Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.P ubmed_Discovery_RA&linkpos=5&log$=relatedarticles& logdbfrom=pubmed

gdje zakljucuju:
"Recent results suggest that the use of long-term prophylactic low-molecular-weight heparin in pregnancy is not associated with a significant decrease in bone mineral density. Whether higher doses might be a risk factor for osteoporosis is still an unanswered question. It is also possible that subgroups are more susceptible. Overall, women should be reassured regarding the risk of osteoporosis associated with the use of prophylactic dose of low-molecular-weight heparin during their pregnancy."