BREAST FEEDING: Loratadine and its metabolite, descarboethoxyloratadine, are excreted into human milk . The AUCmilk/AUCplasma ratio for loratadine and descarboethoxyloratadine were 1.17 and 0.85 respectively in 6 lactating women after ingestion of a single 40 mg dose of loratadine. The peak milk concentration, 29.2 ng/mL, occurred within 2 hours of the dose. A 4-kg infant ingesting the loratadine and descarboethoxyloratadine excreted would have received a dose equivalent to 0.46% of the loratadine dose received by the mother on a mg/kg basis[8].
The American Academy of Pediatrics has classified loratadine as a drug "
Usually Compatible With Breastfeeding" [9].