Timing of hCG administration
The doses of hCG administered are in the range 2000-10,000 IU. The regimen used by many clinics (37) calls for the administration of hCG on the sixth day of a sustained increase in serum estradiol levels. Patients who fail to achieve adequate follicular development after 6-8 days of ovarian stimulation do not receive hCG, and the treatment cycle is cancelled.
In other centres,
hCG is administered when the serum estradiol level reaches 200-300 pg/ml per follicle >17-18 mm in diameter. Patients with poor follicular development or with only one developing follicle are not given hCG. It is inadvisable to give hCG to patients in whom the serum estradiol level is seen to increase rapidly (i.e. doubling in 24 hours) in order to minimize the risk of the OHSS.
Odgovori s citatom